Do computerized clinical decision support systems improve the prescribing of oral anticoagulants? A systematic review.

•Computerized clinical decision support systems (CDSS) might positively impact the prescribing of oral anticoagulant therapy.•CDSS were mainly designed to tackle the issues of anticoagulation underuse and warfarin-drug interactions.•Most systems provided specific recommendations automatically, at the time and location of decision making.•The effect on clinical outcomes remains unclear.