TRAIP promotes malignant behaviors and correlates with poor prognosis in liver cancer.
Biomedicine & Pharmacotherapy（2020）
摘要
•TRAIP is overexpressed in liver cancer and negatively correlated with prognosis.•Knockdown of TRAIP inhibits the malignant behaviors of liver cancer cells.•Knockdown of TRAIP promotes apoptosis and induces cell cycle arrest in liver cancer.•TRAIP is critical for proper mitosis in liver cancer.
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关键词
Liver cancer,TRAF-interacting protein,Cell cycle arrest,Proliferation,Apoptosis
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