The crystal structure of a natural DNA polymerase complexed with mirror DNA.

Jinsu An,Jaewoo Choi,Dohyeon Hwang,Jihyun Park,Charles W Pemble, Thi Hoai Men Duong,Kyoung-Ran Kim,Heechul Ahn,Hak Suk Chung,Dae-Ro Ahn

CHEMICAL COMMUNICATIONS（2020）

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摘要

The intrinsic l-DNA binding properties of a natural DNA polymerase was discovered. The binding affinity of Dpo4 polymerase for l-DNA was comparable to that for d-DNA. The crystal structure of Dpo4/l-DNA complex revealed a dimer formed by the little finger domain that provides a binding site for l-DNA.

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关键词

DNA Structure,DNA nanotechnology

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