π-Extended Donor-Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation.
CHEMISTRY-A EUROPEAN JOURNAL(2020)
摘要
Free base, zinc and palladium pi-extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram-positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex.
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关键词
antimicrobial,photosensitizers,singlet oxygen,triplet state,pi-extended porphyrins
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