Increased activity of the sterol branch of the mevalonate pathway elevates glycosylation of secretory proteins and improves antifungal properties of Trichoderma atroviride.

•Selective activation of squalene synthase by excess of farnesyl pyrophosphate.•Interdependence between the mevalonate pathway activity and protein glycosylation.•Activation of secretory hydrolases by balanced hyper-glycosylation.•Activation of the mevalonate pathway enhancing antifungal activity of Trichoderma.