Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma: A Single Center Experience Of 32 Patients From China

MALT represents the most common subtype in ocular adnexa lymphoma. Little data, however, has been reported in China. We consecutively analyzed 32 patients from April 2008 to January 2016. Median age at diagnosis was 57 (32-90) years. Most patients presented with stage IE (30/32, 87.5%) and the remaining 2 staged IVE. Treatment and followup data were available for 29 patients. Other than resection and biopsy for diagnosis, most of them (20/29, 68.9%) received radiotherapy. The rest underwent chemotherapy (1, 3.5%), both radiotherapy and chemotherapy (2, 6.9%), or 'watch and wait' (6, 20.7%). With a median followup of 28 (6-94) months, all of the patients are alive. Two cases progressed at 24 months and 30 months. Comparing the PFS for four treatment arms, no significant difference can be observed (P=0.147). Our data demonstrated the chronic clinical course and excellent prognosis of OAML. For localized cases, surgery combined with radiotherapy is recommended.