Signature of genome wide gene expression in classical swine fever virus infected macrophages and PBMCs of indigenous vis-a-vis crossbred pigs.

Vaishali Sah,Amit Kumar,P Dhar,V Upmanyu,A K Tiwari,Sajad A Wani,A R Sahu,Ajay Kumar, S K Badasara,Aruna Pandey,Shikha Saxena,Anil Rai,B P Mishra,R K Singh,Ravi Kumar Gandham

Gene（2020）

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摘要

•The IRF7 and RIG1/DDX58 was activated in PBMCs of indigenous pigs at 7dpv.•LAMB1 was downregulated with lower copies of CSF viruses in MDMs of indigenous pig.•Proinflammatory genes were repressed in MDMs of indigenous than crossbred pig.

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CSF,CSFV,PBMC,FCS,GTF,GO,MDMs,DEGs,cELISA,FACS,IPA,BioGRID,FPKM,LABM1,IRF3,NFkB,IL1β,RSEM,BCR,LXR:RXR,TREM-1

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