Immunostimulatory effect of chitosan conjugated green copper oxide nanoparticles in tumor immunotherapy.

Aditi Dey,Subhankar Manna,Sunil Kumar,Sourav Chattopadhyay,Bhaskar Saha,Somenath Roy

Cytokine（2020）

引用 25|浏览14

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摘要

•CuONPs@CS was able to activate the macrophages that killed cancer cells.•Activated macrophages stimulated Th1 & Th2 cells.•Specific antigen conjugated CuONPs@CS functioned as an antigen delivery vehicle.•Antigen conjugated CuONPs@CS triggered cytotoxic T lymphocytes.

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关键词

Surface coated nanoparticles,Macrophage activation,Adjuvant,IgG response,Cytokines

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