Early and later life environmental enrichment affect specific antibody responses and blood leukocyte subpopulations in pigs

•Environmental enrichment affects pigs’ antibody responses and peripheral leukocyte populations.•Early life experience with enrichment has a long-term effect on immunity in pigs.•Enrichment effect on immune parameters depends on early life housing and vice versa.•Early life history and (mis)match with current environment thus important for immunity.•Coping style and sex affected some immune parameters.