Temporal dynamics of Arc/Arg3.1 expression in the dorsal striatum during acquisition and consolidation of a motor skill in mice.

•Arc dynamically expresses in the dorsal striatum during motor skill learning.•Arc level in the DMS increases early and recovers later in training.•Arc level in the DLS elevates gradually and retains later in training.•Arc enriches in striatopallidal neurons in the DMS during early motor learning.•Arc engages in striatonigral neurons in the dorsal striatum later in training.