Effect of Perioperative Low-Dose Dexmedetomidine on Postoperative Delirium After Living-Donor Liver Transplantation: A Randomized Controlled Trial.

•The reported frequency of delirium after liver transplantation (LT) ranges from 12.2% to 47%.•Dexmedetomidine is a recommended sedative for patients in the intensive care unit (ICU), as, it has been associated with less delirium and a shorter duration of delirium compared to benzodiazepines.•Delirium after LT occurred in 9 patients (9%) in the dexmedetomidine group and 6 patients (5.9%) in the control group (P = .44).•Preoperative international normalized ratio for prothrombin time (odds ratio [OR] = 16.23; 95% confidence interval [CI], 4.46-59.03; P < .01), APACHE II score (OR = 1.10; 95% CI, 1.02-1.19; P = .02), and vasopressor support during ICU stay (OR = 13.47; 95% CI, 2.89-62.77; P < .01) were significant predictors of delirium after LT.