Syntheses, Characterization, Crystal Structures, And Antimicrobial Activity Of Oxidovanadium(V) Complexes With Hydrazone And Pyrone Ligands

A pair of new oxidovanadium(V) complexes, [VOLL1] (1) and [VOLL2] (2), where L is the dianionic form of the hydrazone ligand N '-(2-hydroxy-3-methoxybenzylidene)-3-methylbenzohydrazide (H2L), L-1 and L-2 are the deprotonated form of 3-hydroxy-2-methyl-4H-pyran-4-one (HL1) and 3-hydroxy-2-ethyl-4H-pyran-4-one (HL2), respectively, have been prepared and characterized by elemental analyses, IR, UV-Vis, H-1 NMR and single crystal X-ray determination. The V atoms in the complexes are in octahedral coordination, with the hydrazone ligand coordinates to the metal atoms through the phenolate O, imino N, and enolate O atoms, and with the pyrone ligands through the carbonyl and hydroxyl O atoms. The effect of the compounds on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans was studied.