Quality Of Life Impairment In Adult Patients With Acute Lymphoblastic Leukemia With Minimal Residual Disease In France

Introduction: In adult patients with acute lymphoblastic leukemia (ALL), the presence of a minimal residual disease (MRD+), defined as the persistence of tumoral cells at a submicroscopic level, is widely recognized as the most sensitive prognostic factor for relapse and death regardless of treatment choice and risk classification. Although ALL specific treatment guidelines and protocols recommend MRD testing, there is little published literature on how the MRD status would impact on the quality of life (QoL) of adult patients with ALL. This research study aims to describe and assess the impact of MRD status on QoL of different subgroup of adult patients with ALL.