SWI/SNF complex heterogeneity relates with polyphenotypic differentiation, prognosis and immune response in rhabdoid tumors.

Pooja Panwalkar,Drew Pratt,Chan Chung,Derek Dang,Paul Le,Daniel Martinez,Jill M Bayliss,Kyle S Smith,Mike Adam,Steven Potter,Paul Northcott,Leo Mascarenhas,Jared Shows,Bruce Pawel,Ashley Margol,Annie Huang,Alexander R Judkins,Sriram Venneti

Neuro-Oncology（2020）

引用 18|浏览64

暂无评分

摘要

Heterogeneity in SWI/SNF BAF (ACTL6A/ACTL6B) and PBAF (PBRM1) subunits correlates with histogenesis, contributes to the immune microenvironment and prognosis in RTs and may inform opportunities to develop immunotherapies.

查看译文

关键词

AT/RT,Differentiation,Immune infiltration,Rhabdoid tumor,SWI/SNF complex

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要