A tool for designing tree-like concentration gradient generators for lab-on-a-chip applications

Chemical Engineering Science(2020)

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摘要
•TCDT can be used to find CGG dimensions.•TCDT calculates non-linear output concentrations based on the flow at the inlets.•TCDT is ready-to-use for three different CGG microchips.•Food dye is more efficient than fluorescent intensity measurement for multidrug.•MDMC method can be used to find the best concentration for combinatorial drug tests.
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关键词
Tree-like concentration gradient generator,Open-source CGG,Fluorescence measurement,Microfluidics,CFD
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