Bio-guided isolation of new phenolic compounds from Hippocrepis emerus flowers and investigation of their antioxidant, tyrosinase and elastase inhibitory activities

Phytochemistry Letters(2020)

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摘要
•Thirty-two glycosides including flavonoids, phenolic acids and coronillins were identified.•13C NMR-based dereplication was used to identify major compounds of the extracts.•A bioactivity-guided fractionation lead to the isolation of three new triglycosylated flavonoids.•The structures of compounds were determined by 1D and 2D NMR spectra and MS spectra.•Three quercetin glycosides exhibited a significant radical-scavenging activity.
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关键词
Flavonoid,Dereplication,Hippocrepis emerus,Antioxidant,Tyrosinase,Elastase
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