Clonal Competition Models To Understand Progression And Resistance In Myeloma
BLOOD(2019)
摘要
Background: Progression and relapse in Multiple Myeloma (MM) is induced by changes in the clonal tumor composition. In order to better understand the mechanisms underlying these dynamics, we developed clonal competition models based on the co-culture of fluorescent labelled isogenic MM cells, with or without the alteration under study.
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关键词
myeloma,resistance,progression
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