Latent Tuberculosis in Hematopoietic Stem Cell Transplantation: Diagnostic and Therapeutic Strategies to Prevent Disease Activation in an Endemic Population.

Christianne Bourlon,Rocío Camacho-Hernández,Oscar M Fierro-Angulo,Aldo A Acosta-Medina,Maria T Bourlon,María Dolores Niembro-Ortega,María F Gonzalez-Lara,José Sifuentes-Osornio,Alfredo Ponce-de-León

BLOOD（2020）

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摘要

•Infectious complications represent an important limitation for hematopoietic stem cell transplantation (HSCT) outcomes.•Host immunity and diagnostic limitations make latent tuberculosis infection (LTBI) an underestimated problem.•Recipients diagnosed with LTBI could benefit from pre-HSCT treatment.•Prospective data is required to define the best strategies for LTBI in the HSCT setting.

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关键词

Mycobacterium tuberculosis,Hematopoietic stem cell transplantation,Hematologic disease,Tuberculosis

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