A Flexible Strategy For Modular Synthesis Of Curcuminoid-Bf2/Curcuminoid Pairs And Their Comparative Antiproliferative Activity In Human Cancer Cell Lines

A facile protocol that enables synthetic interconversion of CUR-BF2 and CUR compounds is described that significantly widens the preparative scope of curcuminoids, providing access to larger libraries of compounds, thus enabling comparative antiproliferative and apoptotic study of a larger library of synthetic analogs in cancer cell lines.