A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE.

Jean-Rémi Godin,Patrick Roy,Marta Quadri,Deniz Bagdas,Wisam Toma,Ramya Narendrula-Kotha, Osama A Kishta,M Imad Damaj,Nicole A Horenstein,Roger L Papke,Alain R Simard

Brain, Behavior, and Immunity（2020）

引用 38|浏览28

暂无评分

摘要

•Mecamylamine and m-bromo PEP exert anti-inflammatory effects.•Mecamylamine and m-bromo PEP reduce EAE disease severity.•m-bromo PEP reduces CFA-induced inflammatory pain.

查看译文

关键词

Nicotinic acetylcholine receptors,Silent agonism,Inflammation,Experimental autoimmune encephalomyelitis,Inflammatory pain,Cytokines,CNS inflammation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要