Application of new lysine-based peptide dendrimers D3K2 and D3G2 for gene delivery: Specific cytotoxicity to cancer cells and transfection in vitro.

Michal Gorzkiewicz,Malgorzata Konopka,Anna Janaszewska,Irina I Tarasenko,Nadezhda N Sheveleva,Arkadiusz Gajek,Igor M Neelov,Barbara Klajnert-Maculewicz

Bioorganic Chemistry（2020）

引用 60|浏览14

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摘要

•synthesis and purification of novel lysine-based dendritic molecules (D3K2, D3G2)•the dendrimers exhibit specific cytotoxicity towards cancer cells.•D3K2 shows significant transfection efficacy.

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关键词

peptide dendrimers d3k2,gene delivery,cancer cells,lysine-based

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