IMIPMF: Inferring miRNA-disease interactions using probabilistic matrix factorization.

Journal of Biomedical Informatics(2020)

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摘要
•A novel method (IMIPMF) for predicting miRNA-disease associations by using probabilistic matrix factorization was proposed.•IMIPMF achieved a high performance with a comparable AUC value of 0.891 by implementing five-fold cross validation.•The success of IMIPMF in predicting miRNA-disease associations can be explained by its mathematical foundations in MF and the utilization of miRNA expression data.
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关键词
miRNA,Disease,miRNA–disease association,Probabilistic matrix factorization
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