Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 As a Key Selectivity Target.
Zoe A. Henley,Augustin Amour,Nick Barton,Marcus Bantscheff,Giovanna Bergamini,Sophie M. Bertrand,Maire Convery,Kenneth Down,Birgit Duempelfeld,Chris D. Edwards,Paola Grandi,Paul M. Gore,Steve Keeling, Stefano Livia,David Mallett,Aoife Maxwell,Mark Price,Christina Rau,Friedrich B. M. Reinhard,James Rowedder,Paul Rowland, Jonathan A. Taylor,Daniel A. Thomas,Edith M. Hessel,J. Nicole Hamblin Journal of Medicinal Chemistry（2019）
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PI3K/AKT pathway,Therapeutic Targets
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