Preparation of hollow magnetic molecularly imprinted polymer and its application in silybin recognition and controlled release.

Journal of Pharmaceutical and Biomedical Analysis(2020)

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摘要
•A new type of hollow magnetic molecularly imprinted polymer (HMMIP) was prepared by RATRP technology.•An unique hollow structure and favorable magnetic responsivity.•High selectivity and high adsorption capacity on silybin.•The imprinted material had high stability and reproducibility.•HMMIP was evaluated as a drug delivery carrier by performing in vitro release study.
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关键词
Hollow,Magnetic,Silybin,Molecularly imprinted polymer,Sustained released agent
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