Frailty index and phenotype frailty score: sex- and age-related differences in 5XFAD transgenic mouse model of Alzheimer's disease.

Smilja Todorovic,Natasa Loncarevic-Vasiljkovic,Milena Jovic,Srdjan Sokanovic,Selma Kanazir,Aleksandra Mladenovic Djordjevic

Mechanisms of Ageing and Development（2020）

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摘要

•Frailty significantly increases with age in 5xFAD mouse model of AD.•5xFAD females are less frail than 5xFAD males.•Frailty score and frailty index do not identify the same subpopulations as frail.

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关键词

AD,FS,F,MCI,SD,OF,DT,AT,T/AT,DT/AT,V1B

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