MDGA1-deficiency attenuates prepulse inhibition with alterations of dopamine and serotonin metabolism: An ex vivo HPLC-ECD analysis.

Md Razib Hossain,Mostofa Jamal,Yu Tanoue, Daiki Ojima,Hiroo Takahashi,Takashi Kubota, Tuba M Ansary,Asuka Ito,Naoko Tanaka,Hiroshi Kinoshita,Yasushi Kishimoto,Tohru Yamamoto

Neuroscience Letters（2020）

引用 4|浏览23

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摘要

•Mdga1-KO mice displayed significantly reduced levels of PPI.•Mdga1-KO mice also had higher tissue content of HVA and lower tissue content of 5-HIAA.•Norepinephrine, DA, DOPAC and 3-MT levels remained unchanged.

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关键词

MDGA1,Monoamines,Mouse brain,Prepulse inhibition,HPLC-ECD

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