The region-of-interest based measurement selection process for electrical impedance tomography in radiofrequency cardiac ablation with known anatomical information.

•Electrical Impedance Tomography can monitor lesion size in real time during Cardiac Radiofrequency Ablation.•The method balances information needed against a well-posed EIT inverse solver.•It takes advantage of intraprocedural known anatomical information and catheter location derived from anatomic mapping systems.•It was tested in simulation with a real 2.5D thorax boundary and lungs, and an elliptical heart model of 16 mm wall thickness.•It deals well with wide-range tissue background conductivity, varied endocardial convection, catheter location error and EIT noises up to 100 μV.