Gonadotropin-inhibitory hormone in teleosts: new insights from a basal representative, the eel.

G Maugars, J Pasquier,C Atkinson, A-G Lafont,A Campo, N Kamech,B Lefranc,J Leprince,S Dufour,K Rousseau

General and Comparative Endocrinology（2020）

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摘要

•A single gnih paralog has been conserved after the teleost 3R.•The gnih gene encodes three GnIH peptides in a basal teleost, the European eel.•Gnih mRNA is mostly expressed in the diencephalon in the eel.•Eel GnIH peptides inhibit the expression of lhβ, fshβ, gpα and gnrh-r2 in vitro.

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关键词

GnIH,NPVF,Phylogeny,Synteny,Tissue distribution,Pituitary cell culture,Gonadotropin subunits,Pituitary hormones,GnRH-R,Anguilla

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