An analytical method to control the surface density and stability of DNA-gold nanoparticles for an optimized biosensor.

Stephanie Hwu, Manon Garzuel,Csaba Forró,Stephan J Ihle,Andreas M Reichmuth, Fiodar Kurdzesau,János Vörös

Colloids and Surfaces B: Biointerfaces（2020）

引用 23|浏览4

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摘要

•A simple method to quantify the surface density of gold nanoparticles functionalized with DNA.•The DNA surface density on gold nanoparticles can be precisely controlled.•A long-term storage method for DNA functionalized gold nanoparticles results in assay with enhanced reproducibility.

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关键词

DNA functionalization,Gold nanoparticle,Colloid stability,Quantifying ligand density,Snap freezing,Multifunctional colloids

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