Long-course neoadjuvant chemoradiotherapy with versus without a concomitant boost in locally advanced rectal cancer: a randomized, multicenter, phase II trial (FDRT-002)

Jingwen Wang
Jingwen Wang
Yun Guan
Yun Guan
Juying Zhou
Juying Zhou
Chao Li
Chao Li

Radiation Oncology, pp. 1-9, 2019.

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Keywords:
Rectal cancer Neoadjuvant chemoradiotherapy Intensity-modulated radiation therapy

Abstract:

This study was designed to explore whether an intensified chemoradiotherapy (CRT) led to a better clinical outcome in locally advanced rectal cancer. Patients with stage II/III rectal cancer were randomly allocated to receive either pelvic intensity-modulated radiation therapy (IMRT) of 50 Gy/25Fx concurrently with capecitabine and oxalip...More

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