Perturbations in the Activity of Cholinergic Interneurons in the Dorsomedial Striatum Impairs the Update of Actions to an Instrumental Contingency Change.
Neuroscience(2020)
摘要
•The striatal cholinergic interneurons (CINs) are required to update actions to a contingency change.•Inhibition/perturbation of CINs expressing Arch impairs the update of actions.•Online modulation of CINs on the striatal surrounding cells may be the likely mechanism.
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关键词
DMS,ChAT,Cre,CINs,ROC,CDF,ISI,A1→,A2→,RR
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