A metabolomics footprint approach to understanding the benefits of synbiotics in functional foods and dietary therapeutics for health, communicable and non-communicable diseases

•Metabolic Profiling of Probiotic fermented dairy product using NMR spectroscopy.•Identification of biochemical pathways of major and minor metabolic constituents.•Strategy to design synbiotic ferments using Lactic acid bacteria (LAB) co-cultures.•Biochemical basis for anti-microbial activity and epithelial cell binding of LAB.