Effects of postoperative enteral nutrition combined with adjuvant radiotherapy on inflammatory response, nutrition, healing and prognosis in patients receiving radical surgery for esophageal carcinoma.

Purpose: To explore the influence of postoperative enteral nutrition combined with adjuvant radiotherapy on inflammatory response, nutrition, healing and prognosis in patients undergoing radical surgery for esophageal carcinoma. Methods: A total of 114 patients with esophageal carcinoma receiving radical surgery from January 2016 to July 2017 composed the observation group and randomly divided into control group (n=57) and study group (n=57). Patients in the control group were given routine nutritional support after surgery, while those in the study group received enteral nutrition after surgery. The changes in inflammatory response and nutritional level, healing and prognosis in the two groups of patients before and after treatment were compared and analyzed. Results: After treatment, the levels of serum hypersensitive C-reactive protein (hs-CRP) and prostaglandin E (PGE) of patients were decreased in both the control group and study group, and they were lower in the study group than those in the control group, while the levels of serum pro-albumin (PA) and albumin (ALB) of patients in the study group were higher than those in the control group (p<0.05). The postoperative wound healing time, total length of hospital stay, postoperative first exhaust time and defecation time in the study group were shorter than those in the control group (p<0.05). The total incidence rate of postoperative complications of patients in the study group was lower than that in the control group (p<0.05). Conclusion: The application of postoperative enteral nutrition combined with adjuvant radiotherapy in patients subjected to radical surgery for esophageal carcinoma can suppress systemic inflammatory response, improve the nutritional condition, promote postoperative wound healing and improve prognosis and therefore it is worthy of promotion in clinical practice.