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Combined HIV-1 Sequence and Integration Site Analysis Informs Viral Dynamics and Allows Reconstruction of Replicating Viral Ancestors

Sean C. Patro,Leah D. Brandt,Michael J. Bale,Elias K. Halvas,Kevin W. Joseph,Wei Shao,Xiaolin Wu,Shuang Guo,Ben Murrell,Ann Wiegand,Jonathan Spindler,Castle Raley,Christopher Hautman,Michele Sobolewski,Christine M. Fennessey,Wei-Shau Hu,Brian Luke, Jenna M. Hasson,Aurelie Niyongabo,Adam A. Capoferri,Brandon F. Keele, Jeff Milush,Rebecca Hoh,Steven G. Deeks,Frank Maldarelli,Stephen H. Hughes,John M. Coffin,Jason W. Rausch,John W. Mellors,Mary F. Kearney

Proceedings of the National Academy of Sciences（2019）

Cited 89|Views62
Key words
HIV persistence,proviral structure,integration site analysis
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