Cytokines and serum amyloid A in the pathogenesis of hepatitis C virus infection

Sara Abouelasrar Salama,Muriel Lavie,Mieke De Buck,Jo Van Damme,Sofie Struyf

Cytokine & Growth Factor Reviews（2019）

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摘要

•SAA displays anti-viral activity against HCV.•SAA is upregulated via several cytokines namely IL-1, IL-6 and TNF-α.•HCV indirectly upregulates SAA via upregulation of SAA-inducing cytokines.•The interplay between SAA, HCV and lipoproteins may influence HCV infectivity.

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关键词

Cytokines,Serum amyloid A,Hepatitis C virus,IL-1,IL-6,TNF-α

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