Treatment-Related Mortality (Trm) In Children With Down Syndrome (Ds) And B-Lymphoblastic Leukemia (B-All): An Interim Report From The Children'S Oncology Group Trials Aall0932 And Aall1131

Karen R. Rabin,Johann Hitzler,Vilmarie Rodriguez,Reuven Schore,Anne Angiolillo,Michael J. Burke,Wanda Salzer,Kelly Maloney,Xiaomin Lu,Meenakshi Devidas,Mignon L. Loh,Elizabeth Raetz,Stephen P Hunger

BLOOD（2015）

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摘要

Background: Children with DS and B-ALL have historically experienced excessive TRM, primarily from infection. Here we provide an interim report on TRM in children with DS and newly diagnosed B-ALL enrolled on Children's Oncology Group (COG) trials for NCI standard risk (SR) (AALL0932) and high risk (HR) B-ALL (AALL1131).

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