Comparative Proteomic Profiling Of Sera From Patients With Refractory Multiple Myeloma Reveals Pathways And Biomarkers Predicting Response To Bortezomib-Based Therapy

Dominik Dytfeld,Magdalena Luczak,Tomasz Szczepaniak,Anna Przybylowicz-Chalecka,Blazej Ratajczak,Joanna Czerwinska-Rybak,Adam Nowicki,Monika Joks,Andrzej Jakubowiak,Mieczyslaw Komarnicki

BLOOD（2016）

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摘要

Introduction: Identification of drug-resistance biomarkers in multiple myeloma (MM) is a first step to individualization of treatment. Human serum is easily collected and does not require expensive preparation to analyze, therefore it seems the most suitable material to search for biomarkers.

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关键词

multiple myeloma,biomarkers predicting response,bortezomib-based

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