Patient/Donor Cmv Matching Is A Critical Determinant Of Survival In Unrelated Donor Haematopoietic Stem Cell Transplantation

Patients who are CMV seropositive prior to allogeneic stem cell transplantation are well known to have a worse outcome compared to those who are CMV negative. Historically a CMV negative donor was prioritised for all transplant recipients, however in recent years practice has changed to actively search for a CMV positive donor for a positive recipient. Thus matching the CMV status of the patient and donor is considered important.