Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms.

Kirsten Wedervang-Resell,Svein Friis,Vera Lonning,Runar E Smelror,Cecilie Johannessen,Elina J Reponen,Siv H Lyngstad,Tove Lekva,Pål Aukrust,Thor Ueland,Ole A Andreassen,Ingrid Agartz,Anne M Myhre

Psychoneuroendocrinology（2020）

引用 19|浏览41

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摘要

•Adolescents with early-onset psychosis (EOP) have elevated levels of circulating IL-18.•Elevated IL-18/IL-18BP ratio suggest increased activity in the IL-18 system in patients with EOP.•Cortisol and depressive symptoms contributed to the variance in the IL-18/IL-18BP ratio.

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关键词

Cortisol,Immune system,Cytokines,Inflammation,IL-18

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