Preparation and the hemostatic property study of porous gelatin microspheres both in vitro and in vivo.

•Porous gelatin microspheres (PGMs) possess hollow-carved structure.•Hemostatic properties of PGMs were evaluated for the first time in this study.•PGMs can induce red blood cells aggregation and promote fibrin generation.•PGMs have physiological and physical hemostatic mechanisms.