Evaluating the sensitivity of the bovine BCG challenge model using a prime boost Ad85A vaccine regimen.

Lucia Biffar,Laura Blunt, William Atkins,Paul Anderson,Tom Holder,Zhou Xing,Martin Vordermeier,Helen McShane,Bernardo Villarreal-Ramos

Vaccine（2020）

引用 3|浏览17

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摘要

•The BCG challenge model is able to distinguish vaccinated from unvaccinated animals.•The BCG challenge model can be used to discover protective biomarkers.

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关键词

Bovine BCG challenge model,Bovine tuberculosis,Ad85A,BCG Tokyo,Intranodal challenge,Predictors of protection

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