EPIDEMIOLOGY OF HEPATITIS E VIRUS INFECTION IN A COHORT OF 4,023 IMMUNOCOMPROMISED PATIENTS.

Lene H Harritshøj,Christoffer E Hother,Henrik Sengeløv,Gedske Daugaard,Søren S Sørensen,Søren Jacobsen,Michael Perch,Dorte K Holm,Susanne G Sækmose,Bitten Aagaard,Christian Erikstrup,Boris M Hogema,Jens D Lundgren,Henrik Ullum

International Journal of Infectious Diseases（2020）

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摘要

•Hepatitis E virus (HEV) epidemiology was investigated among 4023 immunocompromised patients in Denmark.•The prevalence of HEV RNA was 0.15% and ranged between 0.21% and 0.58% among transplantation patients.•No evidence of chronic HEV infection or transfusion transmission was detected.•The HEV seroprevalence of 22% was not associated with the number of blood transfusions.•HEV seroprevalence was not higher among immunocompromised patients than among age- and sex-matched blood donors.

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关键词

Hepatitis E,Epidemiology,Immunocompromised,Transfusion transmission,HEV RNA,Anti-HEV IgG,Chronic HEV infection

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