CaSR is required for ischemia-induced proliferation and differentiation of white matter progenitor cells from neonatal rats.

Feng-Xia Mao,Cheng-Han Luo,Hui-Jin Chen,Yi-Xia Zhang,Qian Zhang

Brain Research Bulletin（2020）

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摘要

•CaSR induced progenitor cell to proliferate and differentiate into OL precursor.•Silencing CaSR weaken proliferation and differentiation of progenitor cell.•ATP-MgCl2 enhanced proliferation and differentiation of progenitor cell.•ATP-MgCl2 reduced apoptosis of newborn cells.

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关键词

Periventricular leukomalacia,Oxygen-glucose deprivation,Progenitor cell,Calcium-sensing receptor,ATP-MgCl2,Oligodendrocyte

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