Desiccation crisis of saline lakes: A new decision-support framework for building resilience to climate change.

•An eco-hydrological framework is developed to restore desiccating saline lakes.•A wide range of climatic, hydrologic, and agronomic stressors are considered.•Parts of the lake that should be prioritized for restoration can also be identified.•Alternative cropping patterns and land-use change are determined for restoration.•The framework applicability is demonstrated through the case of Lake Urmia in Iran.