Role of sphingolipids in the pathogenesis of intrahepatic cholestasis.

•Intrahepatic cholestasis related perinatal complications include premature birth, meconium-stained amniotic fluid, fetal bradycardia, fetal respiratory distress syndrome and intrauterine fetal demise.•Cholestasis treatment with UDCA is known to be very effective.•Sphingolipids can potentially become screening markers as well as markers for monitoring the treatment of ICP in pregnant women.