Homology Modeling of P2X Receptors.

Anastasios Stavrou,Sudad Dayl,Ralf Schmid

PURINERGIC SIGNALING: METHODS AND PROTOCOLS（2020）

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摘要

Since the X-ray structure of the zebra fish P2X4 receptor in the closed state was published in 2009 homology modeling has been used to generate structural models for P2X receptors. In this chapter, we outline how to use the MODELLER software to generate such structural models for P2X receptors whose structures have not been solved yet.

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关键词

Homology modeling,Ion channel,MODELLER software,P2X receptor,Protein structure prediction

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