ACRNaCT trial protocol: efficacy of adjuvant chemotherapy in patients with clinical T3b/T4, N+ rectal Cancer undergoing Neoadjuvant Chemoradiotherapy: a pathology-oriented, prospective, multicenter, randomized, open-label, parallel group clinical trial

Dakui Luo
Dakui Luo
Lifeng Yang
Lifeng Yang
Qi Liu
Qi Liu
Lei Liang
Lei Liang

BMC Cancer, pp. 1-7, 2019.

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Keywords:
Neoadjuvant chemoradiotherapy Adjuvant chemotherapy Locally advanced rectal cancer Yield pathological stage

Abstract:

The CAO/ARO/AIO-94 demonstrated that neoadjuvant chemoradiotherapy (CRT) could decrease the rate of local recurrence rather than distal metastases in advanced rectal cancer. Adjuvant chemotherapy (ACT) can eliminate micrometastasis, and render a better prognosis to rectal cancer. However, adoption of ACT mainly depends on the evidence fro...More

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