Structure-Based and Property-Driven Optimization of N-Aryl Imidazoles Toward Potent and Selective Oral RORγt Inhibitors.
Klemens Hoegenauer,Joerg Kallen,Eloisa Jimenez-Nunez,Ross Strang,Peter Ertl,Nigel G. Cooke,Samuel Hintermann,Markus Voegtle,Claudia Betschart,Daniel J. J. McKay,Juergen Wagner,Johannes Ottl,Christian Beerli,Andreas Billich,Janet Dawson,Klemens Kaupmann,Markus Streiff,Nathalie Gobeau,Stephanie Harlfinger,Rowan Stringer,Christine Guntermann JOURNAL OF MEDICINAL CHEMISTRY（2019）
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