No Impact on the Incidence Rate of Adenoidectomy 1998-2014 on a National level in Denmark by the Use of Nasal Steroid and the introduction of Pneumococcal Vaccines.

CLINICAL OTOLARYNGOLOGY(2020)

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摘要
Objective To describe trends in incidence rates of adenoidectomy in children in Denmark from 1998-2014 and to look for possible explanatory factors such as intranasal steroids and pneumococcal vaccination. Design A nationwide, population-based, retrospective, interrupted time-series analysis, using data from Danish registries. Setting Hospitals and private Ear, Nose and Throat clinics. Participants Children who underwent adenoidectomy from 1998 to 2014 in Denmark. Main outcome measure Adenoidectomy. Methods The National Patient Register and the National Health insurance Service Register were used to identify all adenoidectomies performed in children. The National Prescription Register supplied data on intranasal steroids. Results A total of 174,557 adenoidectomies were identified, distributed among 153 022 children. The annual incidence rate was stable at around 11 per 1000 person-years from 1998 to 2004. A decrease was seen from 2004 reaching 7.9 in 2009, followed by an increase to 9.1 in 2014. The highest age-specific incidence rates were seen at 2-3 years of age. An estimated 14% of children born in 2014 will have had adenoidectomy performed before turning 16 years old. The proportion of adenoidectomies performed in private clinics compared with hospitals was 90%. Conclusion From 1998 to 2004 the incidence rate of adenoidectomy in children in Denmark was among the highest in the world with around 11 per 1000 person-years. A decrease to 7.9 was seen from 2004 to 2009. We found no inverse correlation on a national level between the incidence rates of adenoidectomy and intranasal steroid, nor the introduction of the pneumococcal vaccine. The amount of intranasal steroids used in children in Denmark was negligible compared with adenoidectomy.
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关键词
adenoid,adenoidectomy,epidemiology,incidence,nasal steroid,pharyngeal tonsils,pneumococcal vaccine
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