Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE.

Edouard Bardou-Jacquet,Emilie Morandeau,Gregory J Anderson,Grant A Ramm,Louise E Ramm,Jeff Morcet,Guillaume Bouzille,Jeannette Dixon,Andrew D Clouston,Fabrice Lainé,Bruno Turlin,Lawrie W Powell,Yves M Deugnier

Clinical Gastroenterology and Hepatology（2020）

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摘要

In a retrospective analysis of patients with hemochromatosis caused by the C282Y mutation in HFE, we found that severe liver fibrosis can regress with treatment. In patients with fibrosis regression to a stage F2 or less, the long-term risk for liver cancer is significantly reduced.

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关键词

HCC,Iron Overload,Outcome,Hepatocellular Carcinoma

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